Shipud writes "We live in the post-genomic era, when DNA sequence data is growing exponentially. However, for most of the genes that we identify, we have no idea of their biological functions. They are like words in a foreign language, waiting to be deciphered. The Critical Assessment of Function Annotation, or CAFA, is a new experiment to assess the performance of the multitude of computational methods developed by research groups worldwide and help channel the flood of data from genome research to deduce the function of proteins. Thirty research groups participated in the first CAFA, presenting a total of 54 algorithms. The researchers participated in blind-test experiments in which they predicted the function of protein sequences for which the functions are already known but haven't yet been made publicly available. Independent assessors then judged their performance. The challenge organizers explain that: 'The accurate annotation of protein function is key to understanding life at the molecular level and has great biochemical and pharmaceutical implications, explain the study authors; however, with its inherent difficulty and expense, experimental characterization of function cannot scale up to accommodate the vast amount of sequence data already available. The computational annotation of protein function has therefore emerged as a problem at the forefront of computational and molecular biology.'"

Lasrick writes "This article starts with an interesting anecdote: 'In 1998, President Bill Clinton read a novel about biological warfare that deeply disturbed him. In fact, the story reportedly kept him up all night. It’s one of the reasons that Clinton became personally invested in protecting the United States from bioterrorism threats. The book was The Cobra Event (Preston, 1998), a sci-fi thriller by journalist and novelist Richard Preston that told of a mad scientist who brewed a lethal, genetically engineered virus in his New York City apartment. Preston’s tale highlighted the potential ease with which individuals or small groups with access to advanced bioweapons capabilities could launch attacks on major US cities.1 After reading The Cobra Event, Clinton called several advisory meetings and ordered classified assessments and simulation exercises to examine the threat depicted in the story. As a result of these deliberations, by the end of his administration Clinton had increased funding for biodefense preparedness efforts fourfold, to more than $400 million per year.' The article goes on to describe the two trajectories of bioweapons threats, and puts them both in perspective. It may or may not calm everyone who's ever spent a sleepless night after reading one of the many bioterrorism novels"

MikeChino writes "Instructables member Patrik has successfully transformed an old HP5150 inkjet printer into a DIY bioprinter. To do this he removed the plastic covers and panels and rewired the paper handling mechanism. Then he prepped ink cartridges to be able to handle biological materials by opening the lid, removing the ink, and washing it out with deionized water. For his first experiment, he printed a simple solution of arabinose onto filter paper."

A reader sends news of researchers who encoded an MP3, a PDF, a JPG, and a TXT file into DNA, along with another file that explains the encoding. The researchers estimate the storage density of this technique at 2.2 petabytes per gram (abstract). "We knew we needed to make a code using only short strings of DNA, and to do it in such a way that creating a run of the same letter would be impossible. So we figured, let's break up the code into lots of overlapping fragments going in both directions, with indexing information showing where each fragment belongs in the overall code, and make a coding scheme that doesn't allow repeats. That way, you would have to have the same error on four different fragments for it to fail – and that would be very rare," said one of the study's authors. "We've created a code that's error tolerant using a molecular form we know will last in the right conditions for 10 000 years, or possibly longer," said another.

theodp writes "Harvard geneticist George Church recently told Der Spiegel he's close to developing the necessary technology to clone a Neanderthal, at which point all he'd need is an 'adventurous human woman' to be a surrogate mother for the first Neanderthal baby to be born in 30,000 years (article in German, translation to English). Church said, 'We have lots of Neanderthal parts around the lab. We are creating Neanderthal cells. Let's say someone has a healthy, normal Neanderthal baby. Well, then, everyone will want to have a Neanderthal kid. Were they superstrong or supersmart? Who knows? But there's one way to find out.'"

cylonlover writes "Inspired by the tough teeth of a marine snail and the remarkable process by which they form, assistant professor David Kisailus at the University of California, Riverside is working toward building cheaper, more efficient nanomaterials. By achieving greater control over the low-temperature growth of nanocrystals (abstract), his research could improve the performance of solar cells and lithium-ion batteries, lead to higher-performance materials for car and airplane frames, and help develop abrasion-resistant materials that could be used for anything from specialized clothing to dental drills."

An anonymous reader writes "Dozens of volunteers who anonymously donated their genomic data to a public database for medical research have been identified by a team led by Yaniv Erlich, a former computer security researcher turned geneticist. Erlich's team matched Y chromosomal markers in genomes compiled by the 1000 Genomes Project with non-anonymous genomic databases, for example some assembled from contributions by family tree enthusiasts (abstract). After finding a match on a presumed relative of the study participant, the researchers pieced together the relative's family tree through search engines and the like, until they were able to identify the participant based on gender, age, place of birth, and other supposedly 'non-identifying' information associated with the genome. The names of the identified participants have not been released."

ananyo writes "The ribosome, the molecular machine that translates our genetic code to build the body's proteins, is a mechanical marvel. Now, chemists have invented a nanomachine that can achieve a similar feat. The artificial system is not about to displace nature's ribosome, a complex of proteins and RNA. It is much simpler, and only about about one-tenth of the size — and, it is achingly slow, destroys the code it reads and can produce only very short chunks of protein, known as peptides. It does, however, show that some of the tactics of biology's molecular machines can be adopted to make useful chemicals. The device relies on a rotaxane — a large molecular ring threaded onto another molecule that acts as an axle (abstract). The axle is lined with three amino acids, and a chain of three more amino acids hangs from the outer edge of the ring. Heating the device prompts the ring to move along the axle, adding amino acids one-by-one to the chain attached to the ring."

Zothecula writes "Fireflies have helped an international team of scientists get over 50 percent more light out of existing LED bulbs. It was discovered that in the Photuris genus of firefly, scales in the insect's exoskeleton possess optical qualities that boost the amount of bioluminescence that can shine through. Those same qualities were found to dramatically increase the light output of an LED bulb."

sciencehabit writes "If carrion flies have one enviable talent, it's finding animal carcasses in the wilderness, something they surpass even the most systematic and intrepid field biologists at doing. Now, researchers may be able to capitalize on the insects' gruesome gift to survey biodiversity. Capture the flies, a new study shows, and DNA from their last meals will tell you which animals live in the area. In addition to scanning an area's biodiversity, the technique has the potential to reveal species that are new to science."

Bruce66423 writes "An article at The Guardian discusses the prospects for food from radically different sources than the ones we're used to. 'Sweet fried crickets' anyone? Quoting: '... artificial steak is still a way off. Pizza toppings are closer. The star of the Dutch research into in-vitro meat, Dr Mark Post, promised that the first artificial hamburger, made from 10bn lab-grown cells, would be ready for "flame-grilling by Heston Blumenthal" by the end of 2012. At the time of writing it is still on the back burner. Post (who previously produced valves for heart surgery) and other Dutch scientists are currently working over the problem of how to turn the "meat" from pieces of jelly into something acceptably structured: an old-fashioned muscle. Electric shocks may be the answer. ... The technological problems of producing the new hi-tech foods are nothing compared to the trouble the industry is having with the consumers – the "yuck factor," as the food technology scientists across the world like to put it. Shoppers' squeamishness has turned the food corporations, from whom the real money for R&D will have to come, very wary, and super-secretive about their work on GM in America.'"

Freddybear writes "Former anti-GMO activist Mark Lynas, who opposed genetically modified food in the 1990s, said recently, at the Oxford Farming Conference: 'I want to start with some apologies. For the record, here and upfront, I apologize for having spent several years ripping up GM crops. I am also sorry that I helped to start the anti-GM movement back in the mid 1990s, and that I thereby assisted in demonizing an important technological option which can be used to benefit the environment. As an environmentalist, and someone who believes that everyone in this world has a right to a healthy and nutritious diet of their choosing, I could not have chosen a more counter-productive path. I now regret it completely. So I guess you'll be wondering — what happened between 1995 and now that made me not only change my mind but come here and admit it? Well, the answer is fairly simple: I discovered science, and in the process I hope I became a better environmentalist.' To vilify GMOs is to be as anti-science as climate-change deniers, he says. To feed a growing world population (with an exploding middle class demanding more and better-quality food), we must take advantage of all the technology available to us, including GMOs. To insist on 'natural' agriculture and livestock is to doom people to starvation, and there’s no logical reason to prefer the old ways, either. Moreover, the reason why big companies dominate the industry is that anti-GMO activists and policymakers have made it too difficult for small startups to enter the field."

Let's say you are an IT stud named Yoed Anis, you spent a year in Japan and decided you really like Saké, and you're back home in Austin, Texas. Since Texas, like Japan, grows lots of rice, you obviously need to start the Texas Saké Company to produce Rising Star and Whooping Crane Sakés, which you sell online and through a number of Texas restaurants and retailers. But whatever we can say in print pales beside a two-part brewery tour conducted by Toji Yoed himself, accompanied by Timothy Lord and his trusty camcorder. Yes, there's a transcription. But the video tour itself is better, even though it regretfully does not include the delightful aroma of Saké being made. (Someday, perhaps, Slashdot Studios will be equipped for Smell-O-Vision, but that's at least a few years off.)

An anonymous reader writes with a story about the possibility of genetically engineered salmon showing up on your table. "A controversial genetically engineered salmon has moved a step closer to the consumer's dining table after the U.S. Food and Drug Administration said Friday the fish didn't appear likely to pose a threat to the environment or to humans who eat it. AquAdvantage salmon eggs would produce fish with the potential to grow to market size in half the time of conventional salmon. If it gets a final go-ahead, it would be the first food from a transgenic animal - one whose genome has been altered - to be approved by the FDA."

dryriver writes "The BBC reports that cosmetic products using bee venom as an ingredient are a new 'hot seller' in the cosmetics market. Bee venom is said to have an effect on female skin similar to Botox injections, tightening the skin and making wrinkles and other signs of aging appear less pronounced than before. Unlike Botox, however, bee venom does not need to be injected, and can be absorbed through the skin naturally as an ingredient of cosmetic skin creme. Now comes the kicker: A special electrified device that causes bees to sting a synthetic membrane and release their venom can harvest about one gram of bee venom from 20 bee hives. That one gram of bee venom is worth a whopping 350 dollars. This makes bee venom almost seven times more valuable than gold, which, in comparison, is worth only about 53 dollars per gram."

An anonymous reader writes in with a story about the possibility of having another you in the future. "Human cloning could happen within the next half century, claims a Nobel Prize-winning scientist. Sir John Gurdon, the British developmental biologist whose research cloning frogs in the 1950s and 60s led to the later creation of Dolly the sheep in 1996, believes that human cloning could happen within the next 50 years. He said that parents who lose their children to tragic accidents might be able to clone replacements in the next few decades. Gurdon, who won this year's Nobel Prize for Physiology or Medicine, said that while any attempts to clone a human would likely raise complex ethical issues, he believes that in the near future people would overcome their concerns if cloning became medically useful."

hugheseyau writes "A new pacemaker has been built inside a heart by converting beating muscle into cells which can organise the organ's rhythm, U.S. researchers report. Scientists injected a genetically-modified virus into guinea pigs to turn part of their heart into a new, working pacemaker."

ananyo writes "DNA strands can be coaxed to fold up into shapes in a matter of minutes, reveals a study published in Science (abstract). The finding could radically speed up progress in the field of DNA origami. DNA origami involves using short DNA strands to hold a longer, folded strand in place at certain points, like sticky tape. Until now, assembling the shape has involved heating the DNA and allowing it to cool slowly for up to a week. But researchers at the Technical University of Munich in Germany have worked out that for most of the cooling period, nothing happens. But when a crucial temperature is reached, the whole structure forms suddenly. The researchers now aim to design nanostructures with optimal folding temperatures close to 37 C, the temperature at which mammalian cell cultures are grown, so that DNA machines could one day be used in biological settings."

angry tapir writes "Researchers in the U.S. have developed integrated circuits that can stick to the skin like a child's tattoo and in some cases dissolve in water when they're no longer needed. The 'bio chips' can be worn comfortably on the body to help diagnose and treat illnesses. The circuits are so thin that when they're peeled away from the body they hang like a sliver of dead skin, with a tangle of fine wires visible under a microscope. Similar circuits could one day be wrapped around the heart like 'an electronic pericardium' to correct irregularities such as arrhythmia."

Press2ToContinue writes "Scientists have found a relatively straightforward way to persuade the cells discarded in human urine to turn into valuable neurons. The technique, described online in a study in Nature Methods this week (abstract), does not involve embryonic stem cells. These come with serious drawbacks when transplanted, such as the risk of developing tumors. Instead, the method uses ordinary cells present in urine, and transforms them into neural progenitor cells — the precursors of brain cells. Researchers routinely reprogram cultured skin and blood cells into induced pluripotent stem cells, which can go on to form any cell in the body. But urine is a much more accessible source."