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+ - Exposing the Machinery of the Resistome-> 1

Submitted by aarondubrow
aarondubrow (1866212) writes "2011 Nobel Prize Winner, Bruce Beutler, is using the Ranger supercomputer at The University of Texas at Austin for an ambitious new project to discover all of the genes involved in the mammalian immune response – the so-called "resistome." Over several years, Beutler's lab will sequence the protein coding portions of genes in 8,000 mice to detect the impact of mutations on immunity. This means scanning, enriching and sequencing 500 billion base pairs every week. The project represents a "Big Data" problem of the highest order."
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Exposing the Machinery of the Resistome

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  • I know that mice are mammalian, same as human, and that there are a lot of genetic similarities shared in between the various types of mammalian

    Assuming a full completion of Dr. Beutler's project, that he has gotten a full picture on how the mice resistome system works, in terms of which genes are involved ... how much of it applies to human?

    And I suspect that even among human beings, the "resistome map" would be slightly different in between that of a person from Europe and one from South America, for exam

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